GenOne is a gentamicin sulfate with betamethasone valerate topical spray that is indicated for the treatment in dogs of infected superficial lesions for bacteria sensitive to gentamicin. Each milliliter contains gentamicin sulfate equivalent to 0.57 mg gentamicin base, and betamethasone valerate equivalent to 0.284 mg betamethasone. Gentamicin, a broad-spectrum antibiotic, is a highly effective topical treatment for bacterial infections of the skin. Betamethasone valerate, a synthetic glucocorticoid, has been shown to provide anti-inflammatory and antipruritic activity in the topical management of corticosteroid-responsive infected superficial lesions in dogs. For topical use in dogs only.