Acepromazine Injectable – 50 ml


Acepromazine Injectable is an injectable tranquilizer for use in dogs, cats, and horses.

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Acepromazine Injectable is a tranquilizer for intravenous, intramuscular or subcutaneous injection.  Acepromazine Maleate Injection, USP, is a potent tranquilizer with a low toxicity useful in the tranquilization of dogs, cats and horses. Made by VetOne.

Additional information

Weight .24 lbs
Dimensions 1.75 x 1.75 x 3.0 in

More Details

Acepromazine Injectable requires a prescription from your veterinarian.

Acepromazine Maleate Injection, USP, a potent neuroleptic agent with a low order of toxicity, is of particular value in the tranquilization of dogs, cats and horses. Its rapid action and lack of hypnotic effect are added advantages.

Each mL contains: acepromazine maleate 10 mg, sodium citrate 0.36%, citric acid 0.075%, benzyl alcohol 1% and water for injection.


Supplied as Acepromazine Maleate Injection 10mg/ml in 50 mL multi-dose vials.


Use as directed by your veterinarian.

Dosage and Administration:  As a general rule, the dosage requirement in mg/lb of body weight decreases as the weight of the animal increases.

Acepromazine Maleate Injection may be given intravenously, intramuscularly or subcutaneously. The following schedule may be used as a guide to IV, IM or SC injections:

Dogs: 0.25-0.5 mg/lb of body weight.

Cats: 0.5-1 mg/lb of body weight.

Horses: 2-4 mg/100 lb of body weight.

IV doses should be administered slowly, and a period of at least 15 minutes should be allowed for the drug to take full effect.


Phenothiazines may potentiate the toxicity of organophosphates and the activity of procaine hydrochloride. Therefore, do not use Acepromazine Maleate Injection to control tremors associated with organic phosphate poisoning. Do not use in conjunction with organophosphorus vermifuges or ectoparasiticides, including flea collars. Do not use with procaine hydrochloride.

Do not use in horses intended for human consumption.

Precautions: Tranquilizers are potent central nervous system depressants and they can cause marked sedation with suppression of the sympathetic nervous system.

Tranquilizers can produce prolonged depression or motor restlessness when given in excessive amounts or when given to sensitive animals.

Tranquilizers are additive in action to the actions of other depressants and will potentiate general anesthesia. Tranquilizers should be administered in smaller doses and with greater care during general anesthesia and also to animals exhibiting symptoms of stress, debilitation, cardiac disease, sympathetic blockade, hypovolemia or shock. Acepromazine Maleate Injection, like other phenothiazine derivatives, is detoxified in the liver; therefore, it should be used with caution in animals with a previous history of liver dysfunction or leukopenia.

Hypotension can occur after rapid intravenous injection causing cardiovascular collapse. Epinephrine is contraindicated for treatment of acute hypotension produced by phenothiazine-derivative tranquilizers since further depression of blood pressure can occur. Other pressor amines, such as norepinephrine or phenylephrine, are the drugs of choice.

In horses, paralysis of the retractor penis muscle has been associated with the use of phenothiazine-derivative tranquilizers. Such cases have occurred following the use of Acepromazine Maleate Injection. This risk should be duly considered prior to the administration of Acepromazine Maleate Injection to male horses (castrated and uncastrated). When given, the dosage should be carefully limited to the minimum necessary for the desired effect. At the time of tranquilization, it is not possible to differentiate between reversible protrusion of the penis (a normal clinical sign of narcosis) and the irreversible paralysis of the retractor muscle. The cause of this side reaction has not been determined. It has been postulated that such paralysis may occur when a tranquilizer is used in conjunction with testosterone (or in stallions).

Accidental intracarotid injection in horses can produce clinical signs ranging from disorientation to convulsive seizures and death.

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