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Prednisolone is a corticosteroid used to treat various inflammatory and allergy conditions as well as other
diseases. It reduces swelling and inflammation which can reduce pain or decrease the possible joint damage that
is caused by chronic inflammation. Prednisolone requires a prescription from your veterinarian, and is sold per
tablet or available as an oral solution.
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Prednisolone is a corticosteroid that is used in dogs and cats to treat hypoadrenocorticism (Addison's disease), and other various conditions such as inflammation from arthritis, allergies and certain autoimmune diseases. Prednisolone reduces swelling and decreases a pet's ability to fight infections. It should be given with food to lessen stomach upset, and should not be stopped suddenly without talking to your veterinarian. There should be a gradual reduction in dosage before stopping as serious side effects may result.
Possible Side Effects
Prednisolone is safe for dogs, but like any medication, there are risks involved. Most common side effects of Prednisolone can include excessive thirst and excessive urination, insomnia, nausea, vomiting, upset stomach, and fatigue. They usually go away when the drug is stopped, but your veterinarian may start you off on a lower dose and slowly increase it to avoid these side effects. However, long-term use of high doses of Prednisolone may lead to serious health conditions, including stomach or intestinal ulcers, perforation, bleeding, diarrhea, lethargy, increased risk of infection, behavior changes, diabetes, or cushing’s disease. If your pet stops eating, or you notice signs such as high fever, black, tarry stools, or bloody vomit, contact your veterinarian immediately.
Drug & Food Interactions
If your pet is on any of the following medications, you should use Prednisolone with caution:
- Amphotericin B - When combined could increase the risk of serious side effects.
- Anticholinesterase - When combined could increase the risk of serious side effects.
- Aspirin - When combined could increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding in the stomach or intestine, ulceration and rarely, perforation.
- Barbiturates - When combined could increase the risk of serious side effects.
- Bupropion - When combined could increase the risk of serious side effects.
- CBD - When combined could increase the risk of serious side effects.
- Cholestyramine - When combined could increase the risk of serious side effects.
- Cyclophosphamide - When combined could increase the risk of serious side effects.
- Cyclosporine - When combined could increase the risk of serious side effects.
- Digoxin - When combined could increase the risk of serious side effects.
- Ephedrine - When combined could increase the risk of serious side effects.
- Estrogens - When combined could increase the risk of serious side effects.
- Insulin - When combined could increase the risk of serious side effects.
- Ketoconazole - When combined could increase the risk of serious side effects.
- Macrolide antibiotics - When combined could increase the risk of serious side effects.
- Mycophenolate - When combined could increase the risk of serious side effects.
- Non-steroidal anti-inflammatory drugs (NSAIDs) - When combined could lead to bleeding in the stomach or intestine. Ulceration could occur.
- Phenobarbital - When combined could increase the risk of serious side effects.
- Rifampin - When combined could increase the risk of serious side effects.
- Warfarin - When combined could increase the risk of serious side effects.
We recommend telling your veterinarian about any medications, supplements, vitamins or herbal pills that your pet is taking.
Pets that are allergic to Prednisolone should not take this medication. It is also not recommended for pets with
viral infections, ulcers, tuberculosis, Cushing’s disease, or systemic fungal infections (unless it’s being used
to treat Addison’s disease). Use the drug with caution for pets with diabetes, heart disease, osteoporosis,
cataracts, high blood pressure, or kidney disease. It should only be used in emergencies for younger animals and
pregnant animals because it can stunt growth or cause ulcers.
If you need to use Prednisone for your pet, always follow your vet’s instructions closely. Never abruptly stop the medication, but instead, slowly transition off of it.
Prednisolone is given to your pet by mouth and with food. The best time to give your pet this medication is
after meal to lessen stomach upset.
Prednisolone dosage depends on the dog's weight, so be sure to check with your vet. If the vet prescribes the medicine more than once daily, keep to the schedule. Never give two doses at a time, because prednisolone overdosing is linked with several severe side effects.
Most vets will only prescribe Prednisolone for a limited time. This is because short-term use of Prednisolone has fewer side effects than long-term use. The longer your dog is given Prednisolone, the higher the chances of developing adverse side effects.
Long-term prescriptions last about three to four months. In critical conditions, the treatment period may increase. Various factors play an essential role in deciding how long your dog stays on Prednisolone. Some long-term uses of Prednisolone will be prescribed for life.
Prednisolone Compounded Oral Liquid should be stored at a room temperature.
The dosage for Prednisolone depends on what condition your dog has, how much they weigh, and what type of
Prednisolone you’re using.
For treatment of Addison’s disease, 0.05 to 0.18 mg per pound of body weight should be given to dogs until the condition is under control.
Once the condition is at a manageable level, your vet will likely decrease the dosage to an amount that will allow your dog to maintain healthy steroid levels. This can be as little as 0.009 mg per pound. Prednisone and prednisolone are usually given in these doses once daily by mouth.
An ideal dosage would be 0.5 milligrams per pound of body weight each day for anti-inflammatory effects. But if you need to suppress your dog’s immune system, it’s possible your vet will prescribe 1 milligram per pound, which is to be given throughout the day.
The exact dosage will be prescribed by your veterinarian.
WHAT IS Prednisolone Compounded Oral Liquid?
Prednisolone Compounded Oral Liquid is an ExpressVet exclusive and is used to treat inflammation and adrenal insufficiency in animals including dogs, cats, and horses.
WHAT ARE THE BENEFITS OF TAKING PREDNISOLONE LIQUID?
The liquid Gabapentin dosage for dogs, cats and horses to used to treat inflammation and adrenal insufficiency.
DOES PREDNISOLONE LIQUID COME IN LIQUID FORM?
Prednisolone is available in liquid form.
PREDNISOLONE LIQUID VS CAPSULE?
HOW MUCH DOES PREDNISOLONE COST?
Prednisolone Liquid price ranges from $43.50 to $67.25 depending on the size ordered.
HOW LONG DOES IT TAKE FOR PREDNISOLONE TO WORK?
This medication works quickly and in about 1 or 2 hours your pet should have relief.
WHAT ARE THE SIDE EFFECTS OF GIVING MY DOG OR PET PREDNISOLONE?
HOW DO I GIVE MY DOG PREDNISOLONE?
The best time to give your pet this medication is after a meal to lessen stomach upset.
WHAT SHOULD I DO IF MY DOG DOES NOT FEEL WELL OR IN CASE OF AN EMERGENCY?
If your pet suddenly has a bad reaction or does not feel well, call your veterinarian immediately or emergency animal services.
CAN PREDNISOLONE MAKE DOGS LEGS WEAK?
WHAT IS COMPOUNDING?
Compounding is a method of preparing individualized prescription medications by licensed pharmacists. Compounding allows the practitioner, the pharmacist, and the pet owner to collaborate to create custom dosages, flavors, and dosage forms for pets to easily, safely, and effectively take their medication. Often pet owners struggle to give oral tablets which is why ExpressVet offers compounded oral liquids, transdermal gels, capsules, and treats to make taking care of your pet easy.
How do I order a compounded prescription medication for my pet?
- Sign in to your existing ExpressVet account, or create a new account.
- Select the item or item(s) you are requesting and add to your cart
- Add your pet’s information and your vet’s information.
- If you are a returning customer, you will see your previous choices available or you can add as new.
- Let us know if you want us to request a prescription from your veterinarian, or if you would like to mail in a prescription.
- Complete your billing, shipping, and payment information at checkout to complete your order.
Do all compounded medications require a prescription?
Yes, all compounded medications require a prescription. Express Vet Pharmacy is happy to request a prescription order from your veterinarian, but all prescription orders must be accompanied by a patient-specific prescription from a licensed veterinarian before an order can be shipped out.
Where is Express Vet licensed to dispense veterinary prescription medications?
We are licensed in 38 states. Alaska (AK), Arizona (AZ), California (CA), Colorado (CO), Connecticut (CT), Delaware (DE), Florida (FL), Hawaii (HI), Illinois (IL), Iowa (IA), Kansas (KS), Kentucky (KY), Massachusetts (MA) ,Michigan (MI), Minnesota (MN), Missouri (MO), Montana (MT), Nebraska (NE), Nevada (NV), New Jersey (NJ), New Mexico (NM), New York (NY), North Dakota (ND), Ohio (OH), Oregon (OR), Pennsylvania (PA), Rhode Island (RI), South Dakota (SD), Tennessee (TN), Texas (TX), Utah (UT), Vermont (VT), Virginia (VA), Washington (WA), West Virginia (WV), and Wisconsin (WI)
Where does ExpressVet source the ingredients for compounding?
All ingredients for compounding are from FDA registered manufacturers and distributors.
How long does it take to process my prescription after the pharmacy receives it?
Once the pharmacy receives authorization to dispense from your veterinarian, compounded medications are prepared and shipped out within 1 to 2 business days.